Kyle Roddick PhD
Kyle Roddick PhD
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Targeted splicing approach for alleviation of a neurexin 1 haploinsufficiency model
NRXN1 encoding the synaptic organizing protein neurexin 1 (Nrxn1) is among the strongest risk genes for autism spectrum disorders as …
Hong Lu
,
Kyle Roddick
,
Long Zuo
,
Peng Zhang
,
Olivia Lam
,
Klara Marsh
,
Rachel O.L. Wong
,
Richard E. Brown
,
Ann Marie Craig
Last updated on Jul 23, 2024
Motor deficits in the McGill-R-Thy1-APP transgenic rat model of Alzheimer’s Disease
The McGill-R-Thy1-APP rat is a transgenic model of Alzheimer’s Disease (AD) which expresses APP with two mutations found in cases of …
Kyle Roddick
,
Heather M. Schellinck
,
Richard E. Brown
Last updated on May 12, 2024
Interval Timing is altered in male Nrxn1+/- mice: Just as in Autism Spectrum Disorder
Autism spectrum disorder (ASD) is characterised by impaired social interaction and communication and increased repetitive and …
Kyle Roddick
,
Elias B. Habib
,
Richard E. Brown
,
Fuat Balcı
Last updated on Dec 31, 2023
Serial Reversal Learning in an Olfactory Discrimination Task in 3xTg-AD Mice
Male and female 3xTg-AD mice between 5 and 24 mo of age and their B6129F2/J wild-type controls were tested on a series of 18 olfactory …
Kyle Roddick
,
Heather M. Schellinck
,
Richard E. Brown
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