Alzheimer's Disease

Motor deficits in the McGill-R-Thy1-APP transgenic rat model of Alzheimer’s Disease
The McGill-R-Thy1-APP rat is a transgenic model of Alzheimer’s Disease (AD) which expresses APP with two mutations found in cases of …
Last updated on May 12, 2024
Intranasal insulin treatment ameliorates spatial memory, muscular strength, and frailty deficits in 5xFAD mice
The 5xFAD mouse model shows age-related weight loss as well as cognitive and motor deficits. Metabolic dysregulation, especially …
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Intranasal insulin treatment ameliorates spatial memory, muscular strength, and frailty deficits in 5xFAD mice
Serial Reversal Learning in an Olfactory Discrimination Task in 3xTg-AD Mice
Male and female 3xTg-AD mice between 5 and 24 mo of age and their B6129F2/J wild-type controls were tested on a series of 18 olfactory …
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Serial Reversal Learning in an Olfactory Discrimination Task in 3xTg-AD Mice
Age Related Weight Loss in Female 5xFAD Mice from 3 to 12 Months of Age
In addition to cognitive decline, patients with Alzheimer’s disease (AD) exhibit sensory, motor, and neuropsychiatric deficits. …
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Age Related Weight Loss in Female 5xFAD Mice from 3 to 12 Months of Age
Sex and Genotype Differences in Odor Detection in the 3×Tg-AD and 5XFAD Mouse Models of Alzheimer's Disease at 6 Months of Age
Deficits in odor identification and detection are early symptoms of Alzheimer’s disease (AD). Two transgenic mouse models of AD, …
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Sex and Genotype Differences in Odor Detection in the 3×Tg-AD and 5XFAD Mouse Models of Alzheimer's Disease at 6 Months of Age
Olfactory Delayed Matching to Sample Performance in Mice: Sex Differences in the 5XFAD Mouse Model of Alzheimer's Disease
While olfactory delayed matching-to-sample tasks have been used to assess working memory in rats, no such tasks have been tested in …
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Olfactory Delayed Matching to Sample Performance in Mice: Sex Differences in the 5XFAD Mouse Model of Alzheimer's Disease