Kyle Roddick PhD
Kyle Roddick PhD
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5XFAD
Intranasal insulin treatment ameliorates spatial memory, muscular strength, and frailty deficits in 5xFAD mice
The 5xFAD mouse model shows age-related weight loss as well as cognitive and motor deficits. Metabolic dysregulation, especially …
William H. Gendron
,
Emre Fertan
,
Kyle Roddick
,
Aimée A. Wong
,
Maria Maliougina
,
Yassine El Hiani
,
Younes Anini
,
Richard E. Brown
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DOI
URL
Age Related Weight Loss in Female 5xFAD Mice from 3 to 12 Months of Age
In addition to cognitive decline, patients with Alzheimer’s disease (AD) exhibit sensory, motor, and neuropsychiatric deficits. …
William H. Gendron
,
Emre Fertan
,
Stephanie Pelletier
,
Kyle Roddick
,
Timothy P. O'Leary
,
Younes Anini
,
Richard E. Brown
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DOI
Sex and Genotype Differences in Odor Detection in the 3×Tg-AD and 5XFAD Mouse Models of Alzheimer's Disease at 6 Months of Age
Deficits in odor identification and detection are early symptoms of Alzheimer’s disease (AD). Two transgenic mouse models of AD, …
Kyle Roddick
,
Amelia D. Roberts
,
Heather M. Schellinck
,
Richard E. Brown
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DOI
Olfactory Delayed Matching to Sample Performance in Mice: Sex Differences in the 5XFAD Mouse Model of Alzheimer's Disease
While olfactory delayed matching-to-sample tasks have been used to assess working memory in rats, no such tasks have been tested in …
Kyle Roddick
,
Heather M. Schellinck
,
Richard E. Brown
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DOI
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